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Bruker Spatial Biology, a division of Bruker Corporation, delivers best‑in‑class solutions for capturing the full complexity of biology. Through a cohesive portfolio of high fidelity instruments, assays, software, and services — each fit-for-purpose for its respective omic and designed to work together as a multiomic ecosystem — Bruker Spatial Biology enables researchers to visualize and quantify biology across DNA, RNA, and protein, generating insights that are difficult to achieve by studying any single omic alone.

The CosMx® Spatial Molecular Imager is built for high sensitivity subcellular imaging of the whole transcriptome for complete pathway-level spatial insights, supported by the AtoMx® Spatial Informatics Platform for AI‑driven 3D cell segmentation and study‑level data exploration. The GeoMx® Digital Spatial Profiler is optimized for unmatched discovery spatial multiomics, combining whole transcriptome analysis with more than 1,200 proteins to profile from cells to tissue structures for spatial breakthroughs at scale. The CellScape™ XR platform is built for flexible, subcellular proteomics for rapid and quantitative spatial phenotyping, while the PaintScape™ platform is optimized for high precision, multiplexed direct visualization of the 3D genome. The nCounter® Analysis System provides highly robust bulk multiomic analysis for rapid biomarker discovery and development.

Together, these solutions are supported by a global team of scientists, sales, and service professionals, along with Bruker Spatial Biology CRO Services for biopharmaceutical research, assay development, and clinical sample testing.

Find the Right Platform for Your Research

PlatformCosMxCellScapeGeoMxnCounterPaintScape
ApplicationsHigh fidelity, high sensitivity, subcellular imaging of the whole transcriptome with proteomics for complete pathway-level spatial insightsHigh fidelity, flexible subcellular proteomics for rapid and quantitative spatial phenotypingHigh fidelity, unmatched discovery multiomics to profile from cells to tissue structures for spatial breakthroughs at scaleRapid and robust targeted RNA and multiomic expression proven for translational and clinical studiesHigh fidelity, high precision multiplexed direct visualization of spatial organization of the 3D genome
AnalyteRNA, proteinProtein, RNARNA, proteinmiRNA, Protein, RNADNA
Plex levelTarget RNA assays (up to 6000 targets)
Whole transcriptome RNA assays
Up to 64 proteins
Targeted protein assays (up to 34 targets)
Customizable assays up to 20
Targeted RNA assays (up to 2000 targets)
Whole transcriptome RNA assays
Up to 1200 proteins
800+ RNA
500+ protein
Targeted DNA Assays (419+ targets)
ResolutionSingle-cell
Subcellular
Single-cell
Subcellular
Multicellular (RNA)
Single-cell (protein)
BulkSingle-nuclei
Sample compatibilityFFPE, FF, organoids, cultured cellsFFPE, FF, cell suspension, lysateFFPE, FFFFPE, FF, lysateHuman cell lines, FF tissue (coming soon)
Data readoutImagingImagingNGS, nCounter (Direct counting)nCounter (Direct counting)Imaging

Our Suppliers

Thermo Scientific Abcam Extragene Favorgen Kapa Biosystems Bruker Spatial Biology Primer Design Meso Scale Discovery Cytoniche Molecular Devices Azure Biosystems