Bruker Spatial Biology CellScape XR Precise Spatial Proteomics
The Next Generation of Multiplexed Spatial Proteomics
Simple, straightforward workflow from sample preparation to image generation
Engineered for flexible, precise spatial proteomics
The highest-quality spatial proteomics platform for precise single-cell phenotyping
Find the Right Platform for Your Research
| Platform | CosMx | CellScape | GeoMx | nCounter | PaintScape |
|---|---|---|---|---|---|
| Applications | High fidelity, high sensitivity, subcellular imaging of the whole transcriptome with proteomics for complete pathway-level spatial insights | High fidelity, flexible subcellular proteomics for rapid and quantitative spatial phenotyping | High fidelity, unmatched discovery multiomics to profile from cells to tissue structures for spatial breakthroughs at scale | Rapid and robust targeted RNA and multiomic expression proven for translational and clinical studies | High fidelity, high precision multiplexed direct visualization of spatial organization of the 3D genome |
| Analyte | RNA, protein | Protein, RNA | RNA, protein | miRNA, Protein, RNA | DNA |
| Plex level | Target RNA assays (up to 6000 targets) Whole transcriptome RNA assays Up to 64 proteins | Targeted protein assays (up to 34 targets) Customizable assays up to 20 | Targeted RNA assays (up to 2000 targets) Whole transcriptome RNA assays Up to 1200 proteins | 800+ RNA 500+ protein | Targeted DNA Assays (419+ targets) |
| Resolution | Single-cell Subcellular | Single-cell Subcellular | Multicellular (RNA) Single-cell (protein) | Bulk | Single-nuclei |
| Sample compatibility | FFPE, FF, organoids, cultured cells | FFPE, FF, cell suspension, lysate | FFPE, FF | FFPE, FF, lysate | Human cell lines, FF tissue (coming soon) |
| Data readout | Imaging | Imaging | NGS, nCounter (Direct counting) | nCounter (Direct counting) | Imaging |
