Applications

MSD's cutting-edge technology provides highly sensitive and robust assays that support the most demanding research applications. We investigate biomarkers identified as promising or critical by organizations such as the Health and Environmental Sciences Institute, the Critical Path Institute, and the Early Detection Research Network of the National Cancer Institute, as well as our own customer base. Select an area of research below to view our targeted single-analyte and multiplex kits.

MSD products support every phase of immunogenicity testing with:

• Superior sensitivity in detecting low- and high-affinity ADAs
• Exceptional intra- and inter-assay precision
• Minimal matrix interference
• A flexible platform that supports most protocols including cell-based neutralizing antibodies
• High drug tolerance that minimizes ADA-drug complex interference
• Wide dynamic range that reduces the need for sample dilutions

Immunogenicity Products
MSD offers an extensive portfolio of assay development kits, plates, and reagents for every stage of biotherapeutic development. MSD products are qualified through rigorous multi-lot testing for reproducibility and precision, and demonstrate exceptional intra-lot and inter-lot consistency.
Products include:
• MSD GOLD Streptavidin Plates – the industry standard for assay performance, consistency, and convenience
• MSD GOLD SULFO-TAG Conjugates – easy to prepare, stable, and result in highly sensitive detection
• MSD GOLD Read Buffer – ready-to-use MSD GOLD Read Buffer delivers even greater lot-to-lot consistency
• ELISA Conversion Packs and U-PLEX Development Packs – extensive development tools that enable users to design custom immunoassays